November 06, 2018 – Breakthrough innovation specialist Cambridge Consultants has designed ‘Verum’, a digital health platform that will reshape the way healthcare is delivered. The platform remotely monitors patients and provides machine learning-driven predictions around conditions or disease states. Verum’s initial test application focuses on clinical trials, where huge efficiencies can be achieved by identifying and mitigating the effect of patient stress on trial outcomes.
Stress is an underlying cause of behavioural and disease states and yet it is poorly characterized, leading to badly controlled clinical trials with average drop-out rates at 30%. For proof of concept, Cambridge Consultants designed a system to measure and monitor a participant’s stress levels during trials. Developed in consultation with clinical psychiatrists and neuroscientists, Verum harnesses the power of biometric data, primarily voice and electromyography (EMG), and machine learning to better understand outcomes and increase the likelihood of clinical success. This machine learning-driven system can provide deeper insight on participants during trials through real-time triggers and alerts, enabling clinicians, nurses and trial co-ordinators to mitigate the effect of stress on compliance, investigate stress as a confounding factor and inform better adaptive trial design through continuous data streams. With the average cost of a Phase 2 clinical trial ranging from $7 million to $19.6 million and 80% of all clinical trials failing to reach completion it’s clear that increased efficiency has the potential to deliver very significant savings.
Verum comprises sensors integrated into a wearable, a data collection app and a widget for healthcare dashboards that augments existing data with patient-specific predictions and alerts, for unprecedented clinical insight. Verum’s ability to provide rich, contextualized biometric information at both population and patient level has the potential to revolutionize precision medicine, post-market surveillance and drug development.
Verum works by enabling clinicians, nurses and trial co-ordinators to access biometric and behavioural data from continuously monitored patients, gaining valuable context around a specific condition. This is achieved by applying a machine learning algorithm to measure patient data, producing a single numerical estimator of a patient’s stress levels at any stage of the trial.
Commenting on Verum, Jaquie Finn, Head of Digital Health at Cambridge Consultants, said: “The rising cost of clinical trials, combined with the commercial risks of failure, mean it’s vital we’re able to harness the power of AI and continuous patient monitoring to mitigate the impact of stress on clinical trial outcomes. Verum informs better adaptive trial design through bigger, real-time contextualized data sets and will mark a step-change in the efficiency of clinical trials.”
Potential future applications of Verum include the diagnosis of neurological conditions, the post market surveillance of drugs, the development of closed loop therapeutics, rehabilitation and remote patient monitoring. Within the consumer space, Verum can enable consumer brands to gain measured, quantitative insights into the use of products during trials. This could accelerate the product development process and provide new insights to spark innovation.
Notes to editors
About Cambridge Consultants and Capgemini
About Cambridge Consultants
Cambridge Consultants develops breakthrough products, services and intellectual property, and provides business consultancy in technology-critical issues for clients worldwide. For more than 60 years, the company has been helping its clients turn business opportunities into commercial successes, whether they are launching first-to-market products, entering new markets or expanding existing markets through the introduction of new technologies. With a team of more than 800 team members, including engineers, scientists, mathematicians and designers, in offices in Cambridge (UK), Boston (USA), Tokyo (Japan) and Singapore, Cambridge Consultants offers solutions across a diverse range of industries including medical technology, industrial and consumer products, digital health, energy and wireless communications.
About Capgemini Invent
As the digital innovation, design and transformation brand of the Capgemini Group, Capgemini Invent enables CxOs to envision and shape the future of their businesses. Located in nearly 40 studios and more than 60 offices around the world, it comprises a 10,000+ strong team of strategists, data scientists, product and experience designers, brand experts and technologists who develop new digital services, products, experiences and business models for sustainable growth.
Capgemini Invent is an integral part of Capgemini, a global leader in partnering with companies to transform and manage their business by harnessing the power of technology. The Group is guided everyday by its purpose of unleashing human energy through technology for an inclusive and sustainable future. It is a responsible and diverse organization of over 325,000 team members in more than 50 countries. With its strong 55-year heritage and deep industry expertise, Capgemini is trusted by its clients to address the entire breadth of their business needs, from strategy and design to operations, fueled by the fast evolving and innovative world of cloud, data, AI, connectivity, software, digital engineering and platforms. The Group reported in 2021 global revenues of €18 billion.
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